Osmium in PDB 3bwf: Crystal Structure of the Human PIM1 in Complex with An Osmium Compound

All present enzymatic activity of Crystal Structure of the Human PIM1 in Complex with An Osmium Compound:
2.7.11.1;

The structure of Crystal Structure of the Human PIM1 in Complex with An Osmium Compound, PDB code: 3bwf was solved by J.Maksimoska, P.Filippakopoulos, S.Knapp, E.Meggers, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.64 / 2.35
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	98.458, 98.458, 81.362, 90.00, 90.00, 120.00
R / Rfree (%)	16.8 / 22.5

The binding sites of Osmium atom in the Crystal Structure of the Human PIM1 in Complex with An Osmium Compound (pdb code 3bwf). This binding sites where shown within 5.0 Angstroms radius around Osmium atom.
In total only one binding site of Osmium was determined in the Crystal Structure of the Human PIM1 in Complex with An Osmium Compound, PDB code: 3bwf:

Osmium binding site 1 out of 1 in the Crystal Structure of the Human PIM1 in Complex with An Osmium Compound


Mono view


Stereo pair view

A full contact list of Osmium with other atoms in the Os binding site number 1 of Crystal Structure of the Human PIM1 in Complex with An Osmium Compound within 5.0Å range: probe atom residue distance (Å) B Occ A:Os315 b:20.0 occ:1.00 OS A:DWC315 0.0 20.0 1.0 C10 A:DWC315 1.9 18.2 1.0 N21 A:DWC315 2.1 13.1 1.0 N19 A:DWC315 2.1 8.3 1.0 C13 A:DWC315 2.2 25.4 1.0 C12 A:DWC315 2.2 16.4 1.0 C17 A:DWC315 2.2 23.4 1.0 C16 A:DWC315 2.2 21.5 1.0 C14 A:DWC315 2.2 23.1 1.0 C22 A:DWC315 2.9 8.3 1.0 C7 A:DWC315 3.0 7.0 1.0 O11 A:DWC315 3.0 22.6 1.0 C6 A:DWC315 3.1 13.6 1.0 C23 A:DWC315 3.3 8.3 1.0 C24 A:DWC315 4.0 7.0 1.0 C29 A:DWC315 4.2 15.3 1.0 C3 A:DWC315 4.3 16.0 1.0 C5 A:DWC315 4.4 19.1 1.0 C28 A:DWC315 4.4 4.1 1.0 CD1 A:ILE185 4.5 8.6 1.0 CZ A:PHE49 4.6 13.8 1.0 O A:HOH323 4.8 43.0 1.0 C4 A:DWC315 4.9 17.0 1.0 CE1 A:PHE49 4.9 10.0 1.0

J.Maksimoska, D.S.Williams, G.E.Atilla-Gokcumen, K.S.Smalley, P.J.Carroll, R.D.Webster, P.Filippakopoulos, S.Knapp, M.Herlyn, E.Meggers. Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes. Chemistry V. 14 4816 2008.
ISSN: ISSN 0947-6539
PubMed: 18425743
DOI: 10.1002/CHEM.200800294